Why Do Women Get More Migraines than Men?

Looking For The Light

Posted on August 27, 2018 by Staff

Researchers have found a potential mechanism for migraine that may explain why women get more migraines than men. The study, inFrontiers in Molecular Biosciences, suggests that sex hormones affect cells around the trigeminal nerve and connected blood vessels in the head. They found that estrogens, which are at their highest levels in women of reproductive age, are particularly important for sensitizing these cells to migraine triggers.

“We can observe significant differences in our experimental migraine model between males and females and are trying to understand the molecular correlates responsible for these differences,” explainsProfessor Antonio Ferrer-Montielfrom the Universitas Miguel Hernández, Spain. “Although this is a complex process, we believe that modulation of the trigeminovascular system by sex hormones plays an important role that has not been properly addressed.”

Ferrer-Montiel and his team reviewed decades of literature on sex hormones, migraine…

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